This paper combs the historical process of campus construction in China, and discusses the logical relationship and internal connection between campus space quality and humanistic spirit construction. This paper reviews the construction and development of the university campus in the peak period of our country, discusses the cultural inheritance of the mountain university campus construction, the Chinese traditional humanistic spirit and development, the enlightenment of western educational thought, and analyzes the nurturing effect and health value of the excellent campus environment construction on the humanistic spirit. The synchronous development of the material environment and the spiritual and cultural environment in campus construction is similar to the law of urbanization development in China. When the material environment construction enters the middle and later stages, it will develop towards refinement and quantification. The improvement of cultural quality and spiritual content has become a new aspect and growth point in the development of urbanization. China’s social and economic development has entered a new normal, and university campuses have entered a stage of coordinated development where the improvement of “space quality” and the construction of “humanistic spirit” go hand in hand. With the optimization of discipline quality, the construction of campus culture, the construction of students’ spiritual outlook, and the construction of the party’s ideological and political education, the construction of the cultural environment of the campus is reaching a new level. Citing the practice cases of the new city construction of Chongqing University, the Huxi new campus construction of Chongqing University and the Yongchuan campus construction of Chongqing City Science and Technology College, this paper further demonstrates the important role of mountain university campus and landscape environment construction in shaping campus quality and its scientific and cultural value. As the material carrier of higher education, the university campus is a place that comprehensively reflects the quality and academic level of school education. In the new historical period when the state proposes to rejuvenate the country through science and technology and strengthen the country through education, the development and improvement of the quality of science and technology and talent education are clearly reflected in all aspects of the country’s comprehensive development of society, economy, science and technology, culture, and art. At present, China’s university education and university construction are further showing a prosperous situation, which is an important part of the national education and science and technology undertakings to maintain high-quality development and competitiveness in the world, promote the level of scientific and technological construction andtalent development in China, and stimulate the development of internal circular economy and culture. The construction of the physical environment and the cultural environment of the university campus are two aspects of equal importance. Education and the construction of university campuses can be understood as a very important part of the “cultural form” of the city. Universities are places for imparting cultural knowledge and spiritual education, and universities have the dual value roles of “material” and “spiritual”. The function of the university is not only to cultivate all kinds of talents needed by the society once a year, but more importantly, to echo the cultural behavior of the university and the urban society, and to contribute to the city’s knowledge innovation, cultural education, and social development. Campus culture and urban culture influence each other to promote the healthy and innovative development of “citizen culture”. From the historical process of the construction and development of China’s campus, the cultural connotation of landscape campus construction, and the campus construction such as Chongqing University, this paper expresses the core point of the paper: the university is the hub core and the first good place for the construction of science and humanities, and the construction of the university campus especially needs to reflect the dual connotation and thought of space quality and humanistic spirit, so as to guide our students, consult and educate our teachers, beautify our campus, and grow and cultivate generations of talents who are physically and mentally healthy, excellent in character and learning. At the end of the paper, the academic point of view is expressed: university is the hub core and the first good place for science and humanities construction, and the construction of university campus especially needs to reflect the dual connotation and thought of space quality and humanistic spirit, so as to guide our students, train our teachers, beautify and shape the campus characteristic environment, and cultivate the talents with physical and mental health and excellent character and study.