Under the background of globalization and industrialization, the disordered city construction and aimless copying reflect the decline of city features. Constructions which adapt to the local natural environment and urban functions, and inherit the historical context of urban form regional characteristics are of great significance. This paper summarizes the concept of urban form regional characteristics elements, with the examples of Langzhong, Leshan, Yibin and Dujiangyan to explore the perception of urban form regional characteristic and build the content framework of the overall urban design based on the urban form regional characteristics. With Hejiang’s new district in Luzhou as an example, the paper excavates the urban natural geographical features, controls regional characteristics of design from the macro level to micro level, and provides certain help for the shape of the sustainable development of urban form and for the same type of overall urban design.