The planning approach of spatial layout pattern based on protecting the hydrological process highlights the spatial integrity involving both the environment and built form, and reduces the intrusion to water environment, and enables the environmental function and ecological service to human settlements. Associated concepts and methods of planning to protect the hydrological process are explicitly unfolded in combination with the case study. Through combing watershed ecological process, conservation and utilization of natural elements, structure of low-carbon construction measures, this paper explicitly addresses the responses to hydrological process protecting three aspects of landuse, site design and built form layout pattern: deepen the analysis of hydrological process and environmental resources, and promote the organic collaboration between the natural hydrological environment efficiency and design management; protect the high value of natural vegetation community, soil environment and natural drainage pattern; the match among land use function, hydrological process and resource characteristics; the design response to microtopography and the implantation of green infrastructure.